Full abstract
Do Intra-operative findings predict patient outcomes of endoscopic sinus surgery?
Presenter: Anna Kaleva
Coauthors: S.H. Rossi, M. A. Salam,
Institute: Ipswich Hospital

Introduction
Functional endoscopic sinus surgery has been proven to be an effective treatment for patient with chronic rhinosinusitis with (CRSwNP) or without nasal polyps (CRSssNP). As well as polyps, a common intra-operative finding is pus in the sinuses. We present prospectively collected data on the outcomes for these patients as measured with the validated SNOT-22 score.
Methods
Data was prospectively collected of all patients who underwent endoscopic sinus surgery between October 2014 and October 2016. Pre- and post-operative data (at 6 weeks and 6 months) was collected in the form of the SNOT-22 questionnaire. A complete dataset was available for 197 patients. Wilcoxon paired Signed Ranks Test was used for nonparametric paired data and Mann-Whitney test for subgroup analysis.
Results
197 patients were included in the final analysis: 74 female patients, 118 patients with nasal polyps and 57 patients with pus present intra-operatively. CRSwNP patients had lower scores than CRSssNP patients pre-operatively (p=0.037), at 6 weeks post-operatively (p=0.023) and at 6 months post-operatively (p=0.001). However, there was no difference in the median of change in scores at either time point. Pre-operatively patients who went on to have pus intra-operatively did not have different score from those without pus. However, at 6 weeks, these patients have significantly lower median scores (p=0.030). This difference however is not seen at 6 months post-operatively (p=0.802).
Conclusion
Our results show that presence/absence of polyps at the time of surgery does not correlate with a different outcome, but the presence of pus correlates with statistically significantly better early post-operative outcome.